Skip to Main Content
  • Instructor Site
  • Student Store
  • United States StoreUnited States
Student store Macmillan learning linkStudent Store Student store Macmillan learning linkStudent Store
    • I'M AN INSTRUCTOR

    • I'M A STUDENT
  • Student store Help link
  • search

    Find what you need to succeed.

    search icon
  • Shopping Cart
    0
    • United States StoreUnited States
  • Who We Are

    Who We Are

    back
    • Who We Are
  • Student Benefits

    Student Benefits

    back
    • Rent and Save
    • Flexible Formats
    • College Quest Blog
  • Discipline

    Discipline

    back
    • Astronomy Biochemistry Biology Chemistry College Success Communication Economics Electrical Engineering English Environmental Science Geography Geology History Mathematics Music & Theater Nutrition and Health Philosophy & Religion Physics Psychology Sociology Statistics Value
  • Digital Products

    Digital Products

    back
    • Achieve
    • E-books
    • iClicker Student App (Student Response System)
    • FlipIt
    • WebAssign
  • Support

    Support

    back
    • Get Help
    • Rental Returns
    • Student Options Explained
    • Support Community

Cover: Lehninger Principles of Biochemistry, 8th Edition by David L. Nelson; Michael M. Cox
Rental FAQs

Lehninger Principles of Biochemistry

Instant Access
info icon

Eighth  Edition|©2021  David L. Nelson; Michael M. Cox

  • Format
  • Packages
E-book from C$86.99

ISBN:9781319322342

Take notes, add highlights, and download our mobile-friendly e-books.

C$86.99
Subscribe until 11/13/2025

C$129.99
Achieve Essentials C$50.00

ISBN:9781319401962

Study, practice, and succeed in your course.

C$50.00
Subscribe until 10/17/2025

You will need to find your course in order to purchase Achieve.

A grace period may be available for this course.

Visit Achieve to find out.

Achieve C$124.99

ISBN:9781319230890

Online course materials that will help you in this class. Includes access to e-book and iClicker Student.

C$124.99
Subscribe until 10/17/2025

You will need to find your course in order to purchase Achieve.

A grace period may be available for this course.

Visit Achieve to find out.

Loose-Leaf C$209.99

ISBN:9781319381479

Save money with our hole-punched, loose-leaf textbook.

C$209.99
Paperback from C$70.00

ISBN:9781319228002

Read and study old-school with our bound texts.

C$70.00
Rent until 11/16/2025

Includes eBook Trial Access

(14-day)


C$140.00
Rent until 05/15/2026

Includes eBook Trial Access

(14-day)


C$399.99

Includes eBook Trial Access

(14-day)

Loose-Leaf + Achieve from C$174.99

This package includes Achieve and Loose-Leaf.

C$174.99

You will need to find your course in order to purchase Achieve.


C$236.99

You will need to find your course in order to purchase Achieve.

Loose-Leaf + Achieve Essentials C$105.99

ISBN:9781319468903

This package includes Achieve Essentials and Loose-Leaf.

C$105.99

You will need to find your course in order to purchase Achieve.

Paperback + Achieve from C$119.99

This package includes Achieve and Paperback.

C$119.99
Rent until 09/27/2025

Includes eBook Trial Access

(14-day)

You will need to find your course in order to purchase Achieve.


C$405.99

Includes eBook Trial Access

(14-day)

You will need to find your course in order to purchase Achieve.


C$134.99
Rent until 09/27/2025

Includes eBook Trial Access

(14-day)

You will need to find your course in order to purchase Achieve.


C$411.99

Includes eBook Trial Access

(14-day)

You will need to find your course in order to purchase Achieve.

  • About
  • Digital Options
  • Contents
  • Authors

About

Clear and coherent.  This is the definitive biochemistry text to learn from and keep as a reference!

Lehninger’s Principles of Biochemistry 8th edition brings clarity and coherence to the complex discipline of biochemistry. An organization that emphasizes the fundamental principles, helps you not simply learn biochemistry but understand it.  The inclusion of cutting-edge discoveries, special themes and biomedical applications make this a truly fascinating resource to learn from.

Digital Options

E-book

Read online (or offline) with all the highlighting and notetaking tools you need to be successful in this course.

Learn More

Achieve Essentials

Complete assignments, engage with course materials, prepare for exams and more in order to succeed in class.

Learn More

Achieve

Achieve is a single, easy-to-use platform proven to engage students for better course outcomes

Learn More

Contents

Table of Contents

Preface viii
1. The Foundations of Biochemistry

I STRUCTURE AND CATALYSIS
2. Water, the Solvent of Life
3. Amino Acids, Peptides, and Proteins
4. The Three-Dimensional Structure of Proteins
5. Protein Function
6. Enzymes
7. Carbohydrates and Glycobiology
8. Nucleotides and Nucleic Acids
9. DNA-Based Information Technologies
10. Lipids
11. Biological Membranes and Transport
12. Biochemical Signaling

II BIOENERGETICS AND METABOLISM
13. Introduction to Metabolism
14. Glycolysis, Gluconeogenesis, and the Pentose Phosphate Pathway
15. The Metabolism of Glycogen in Animals
16. The Citric Acid Cycle
17. Fatty Acid Catabolism
18. Amino Acid Oxidation and the Production of Urea
19. Oxidative Phosphorylation
20. Photosynthesis and Carbohydrate Synthesis in Plants
21. Lipid Biosynthesis
22. Biosynthesis of Amino Acids, Nucleotides, and Related Molecules
23. Hormonal Regulation and Integration of Mammalian Metabolism

III INFORMATION PATHWAYS
24. Genes and Chromosomes
25. DNA Metabolism
26. RNA Metabolism
27. Protein Metabolism
28. Regulation of Gene Expression

Abbreviated Solutions to Problems
Glossary

Authors

David L. Nelson

David L. Nelson, born in Fairmont, Minnesota, received his BS inchemistry and biology from St. Olaf College in 1964, and earned his PhD inbiochemistry at Stanford Medical School, under Arthur Kornberg. He was apostdoctoral fellow at the Harvard Medical School with Eugene P. Kennedy,who was one of Albert Lehninger’s first graduate students. Nelson joinedthe faculty of the University of Wisconsin–Madison in 1971 and became afull professor of biochemistry in 1982. For eight years he was Director ofthe Center for Biology Education at the University of Wisconsin–Madison. Hebecame Professor Emeritus in 2013. Nelson’s research focused on the signaltransductions that regulate ciliary motion and exocytosis in the protozoanParamecium. For 43 years he taught (with Mike Cox) an intensive survey ofbiochemistry for advanced biochemistry undergraduates in the life sciences.He has also taught graduate courses on membrane structure and function, aswell as on molecular neurobiology. He has received awards for hisoutstanding teaching, including the Dreyfus Teacher–Scholar Award and theAtwood Distinguished Professorship. In 1991–1992 he was a visitingprofessor of chemistry and biology at Spelman College. Nelson’s second loveis history, and in his dotage he teaches the history of biochemistry andcollects antique scientific instruments.


Michael Cox

Michael M. Cox was born in Wilmington, Delaware. In his first biochemistry course, the first edition of Lehninger's Biochemistry was a major influence in refocusing his fascination with biology and inspiring him to pursue a career in biochemistry. After graduate work at Brandeis University with William P. Jencks and post-doctoral work at Stanford with I. Robert Lehman, he moved to the University of Wisconsin–Madison in 1983. He became a full professor of Biochemistry in 1992.

Mike Cox has coordinated an active research team at Wisconsin investigating the function and mechanism of enzymes that act at the interface of DNA replication, repair, and recombination. That work has resulted in over 200 publications to date.

For more than three decades, Cox has taught introductory biochemistry to undergraduates and has lectured in a variety of graduate courses. He organized a course on professional responsibility for first-year graduate students and established a systematic program to draw talented biochemistry undergraduates into the laboratory at an early stage of their college career. He has received multiple awards for both his teaching and his research, including the Eli Lilly Award in Biological Chemistry, election as an AAAS fellow, and the UW Regents Teaching Excellence Award. Cox's hobbies include turning 18 acres of Wisconsin farmland into an arboretum, wine collecting, and assisting in the design of laboratory buildings.


The authoritative reference, written with a framework for understanding.

Clear and coherent.  This is the definitive biochemistry text to learn from and keep as a reference!

Lehninger’s Principles of Biochemistry 8th edition brings clarity and coherence to the complex discipline of biochemistry. An organization that emphasizes the fundamental principles, helps you not simply learn biochemistry but understand it.  The inclusion of cutting-edge discoveries, special themes and biomedical applications make this a truly fascinating resource to learn from.

E-book

Read online (or offline) with all the highlighting and notetaking tools you need to be successful in this course.

Learn More

Achieve Essentials

Complete assignments, engage with course materials, prepare for exams and more in order to succeed in class.

Learn More

Achieve

Achieve is a single, easy-to-use platform proven to engage students for better course outcomes

Learn More

Table of Contents

Preface viii
1. The Foundations of Biochemistry

I STRUCTURE AND CATALYSIS
2. Water, the Solvent of Life
3. Amino Acids, Peptides, and Proteins
4. The Three-Dimensional Structure of Proteins
5. Protein Function
6. Enzymes
7. Carbohydrates and Glycobiology
8. Nucleotides and Nucleic Acids
9. DNA-Based Information Technologies
10. Lipids
11. Biological Membranes and Transport
12. Biochemical Signaling

II BIOENERGETICS AND METABOLISM
13. Introduction to Metabolism
14. Glycolysis, Gluconeogenesis, and the Pentose Phosphate Pathway
15. The Metabolism of Glycogen in Animals
16. The Citric Acid Cycle
17. Fatty Acid Catabolism
18. Amino Acid Oxidation and the Production of Urea
19. Oxidative Phosphorylation
20. Photosynthesis and Carbohydrate Synthesis in Plants
21. Lipid Biosynthesis
22. Biosynthesis of Amino Acids, Nucleotides, and Related Molecules
23. Hormonal Regulation and Integration of Mammalian Metabolism

III INFORMATION PATHWAYS
24. Genes and Chromosomes
25. DNA Metabolism
26. RNA Metabolism
27. Protein Metabolism
28. Regulation of Gene Expression

Abbreviated Solutions to Problems
Glossary

Headshot of David L. Nelson

David L. Nelson

David L. Nelson, born in Fairmont, Minnesota, received his BS inchemistry and biology from St. Olaf College in 1964, and earned his PhD inbiochemistry at Stanford Medical School, under Arthur Kornberg. He was apostdoctoral fellow at the Harvard Medical School with Eugene P. Kennedy,who was one of Albert Lehninger’s first graduate students. Nelson joinedthe faculty of the University of Wisconsin–Madison in 1971 and became afull professor of biochemistry in 1982. For eight years he was Director ofthe Center for Biology Education at the University of Wisconsin–Madison. Hebecame Professor Emeritus in 2013. Nelson’s research focused on the signaltransductions that regulate ciliary motion and exocytosis in the protozoanParamecium. For 43 years he taught (with Mike Cox) an intensive survey ofbiochemistry for advanced biochemistry undergraduates in the life sciences.He has also taught graduate courses on membrane structure and function, aswell as on molecular neurobiology. He has received awards for hisoutstanding teaching, including the Dreyfus Teacher–Scholar Award and theAtwood Distinguished Professorship. In 1991–1992 he was a visitingprofessor of chemistry and biology at Spelman College. Nelson’s second loveis history, and in his dotage he teaches the history of biochemistry andcollects antique scientific instruments.


Headshot of Michael Cox

Michael Cox

Michael M. Cox was born in Wilmington, Delaware. In his first biochemistry course, the first edition of Lehninger's Biochemistry was a major influence in refocusing his fascination with biology and inspiring him to pursue a career in biochemistry. After graduate work at Brandeis University with William P. Jencks and post-doctoral work at Stanford with I. Robert Lehman, he moved to the University of Wisconsin–Madison in 1983. He became a full professor of Biochemistry in 1992.

Mike Cox has coordinated an active research team at Wisconsin investigating the function and mechanism of enzymes that act at the interface of DNA replication, repair, and recombination. That work has resulted in over 200 publications to date.

For more than three decades, Cox has taught introductory biochemistry to undergraduates and has lectured in a variety of graduate courses. He organized a course on professional responsibility for first-year graduate students and established a systematic program to draw talented biochemistry undergraduates into the laboratory at an early stage of their college career. He has received multiple awards for both his teaching and his research, including the Eli Lilly Award in Biological Chemistry, election as an AAAS fellow, and the UW Regents Teaching Excellence Award. Cox's hobbies include turning 18 acres of Wisconsin farmland into an arboretum, wine collecting, and assisting in the design of laboratory buildings.


Related Titles

Find Your School

Select Your Discipline

Select Your Course

search icon
No schools matching your search criteria were found !
No active courses are available for this school.
No active courses are available for this discipline.
Can't find your course?

Find Your Course

Confirm Your Course

Enter the course ID provided by your instructor
search icon

We found the following course. Does this look correct?

We found the following course. To properly enroll in your course, please use the link provided in your school's course system (LMS Example: Canvas, Blackboard, D2L, Etc).

Your Achieve account needs to be linked with your school's account.

Find Your School

Select Your Course

No schools matching your search criteria were found.
(Optional)
Select Your Course
No Courses found for your selection.
  • macmillanlearning.com
  • // Privacy Notice
  • // Ads & Cookies
  • // Terms of Purchase/Rental
  • // Terms of Use
  • // Piracy
  • // Products
  • // Site Map
  • // Customer Support
Student store Footer Logo
  • macmillan learning facebook
  • macmillan learning twitter
  • macmillan learning youtube
  • macmillan learning linkedin
  • macmillan learning instagram
We are processing your request. Please wait...