Cover: Coalescent Theory, 1st Edition by John Wakeley

Coalescent Theory

First  Edition©2009  John Wakeley

ISBN:9780974707754

About

Coalescent theory provides the foundation for molecular population genetics and genomics. As an informative and useful text, Coalescent Theory focuses on why this theory is the conceptual framework that makes studies of DNA sequence variation within species possible and how it works as a tool for making inferences about mutation, recombination, population structure and natural selection from DNA sequence data.

Table of Contents

1. Gene Genealogies
2. Probability Theory
3. The Coalescent
4. Neutral Genetic Variation
5. The Structured Coalescent
6. Separation of Time Scales
7. Ancestral Graphs
8. Simulations and Inference
Bibliography
Index

John Wakeley

John Wakeley is Professor and Chairman of Biology at Harvard University. He has worked extensively in coalescent theory. His research has focussed on populations structured by geography and limited migration. Using coalescent models, Dr. Wakeley has addressed questions about the current and historical demography of humans and other species. In May 2004, Dr. Wakeley received a 2002 Presidential Early Career Award for Scientists and Engineers.