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Biology: How Life Works by James Morris; Daniel Hartl; Andrew Knoll; Robert Lue; Melissa Michael; Andrew Berry; Andrew Biewener; Brian Farrell; N. Michele Holbrook; Jean Heitz; Mark Hens; John Merrill; Randall Phillis; Debra Pires; Elena Lozovsky - Third Edition, 2019 from Macmillan Student Store
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Biology: How Life Works

Third  Edition|©2019  James Morris; Daniel Hartl; Andrew Knoll; Robert Lue; Melissa Michael; Andrew Berry; Andrew Biewener; Brian Farrell; N. Michele Holbrook; Jean Heitz; Mark Hens; John Merrill; Randall Phillis; Debra Pires; Elena Lozovsky

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  • About
  • Digital Options
  • Contents
  • Authors

About

Teaching you to think like a biologist, Biology: How Life Works provides you with the best resources to grasp modern biology. The text centers around six crucial themes--the scientific method, chemical and physical principles, cells, evolution, ecological systems, and human impact.

Also Available: Previous 2nd Edition

Digital Options

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Read online (or offline) with all the highlighting and notetaking tools you need to be successful in this course.

Learn More

Achieve

Achieve is a single, easy-to-use platform proven to engage students for better course outcomes

Learn More

Launchpad

Get the e-book, do assignments, take quizzes, prepare for exams and more, to help you achieve success in class.

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Contents

Table of Contents

1. Life: Chemical, Cellular and Evolutionary Foundations

Case 1. The First Cell: Information, Homeostasis, and Energy

2. The Molecules of Life
3. Nucleic Acids and Transcription
4. Translation and Protein Structure
5. Organizing Principles: Lipids, Membranes, and Cell Compartments
6. Making Life Work: Capturing and Using Energy
7. Cellular Respiration: Harvesting Energy from Carbohydrates and Other Fuel Molecules
8. Photosynthesis: Using Sunlight to Build Carbohydrates

Case 2. Cancer: Cell Signaling, Form, and Division

9. Cell Signaling
10. Cell and Tissue Architecture: Cytoskeleton, Cell Junctions, and Extracellular Matrix
11. Cell Division: Variations, Regulation, and Cancer

Case 3. Your Personal Genome: You, from A to T

12. DNA Replication and Manipulation
13. Genomes
14. Mutation and Genetic Variation
15. Mendelian Inheritance
16. Inheritance of Sex Chromosomes, Linked Genes, and Organelles
17. The Genetic and Environmental Basis of Complex Traits
18. Genetic and Epigenetic Regulation
19. Genes and Development

Case 4. Malaria: Coevolution of Humans and a Parasite

20. Evolution: How Genotypes and Phenotypes Change Over Time
21. Species and Speciation
22. Evolutionary Patterns: Phylogeny and Fossils
23. Human Origins and Evolution

Case 5. The Human Microbiome: Diversity Within

24. Bacteria and Archaea
25. Eukaryotic Cells: Origins And Diversity
26. Being Multicellular

Case 6. Agriculture: Feeding a Growing Population

27. Plant Form, Function, and Evolutionary History
28. Plant Reproduction: Finding Mates and Dispersing Offspring
29. Plant Growth and Development
30. Plant Defense
31. Plant Diversity
32. Fungi

Case 7. Biology-Inspired Design: Using Nature to Solve Problems

33. Animal Form, Function, and Evolutionary History
34. Animal Nervous Systems
35. Animal Movement: Muscles and Skeletons
36. Animal Endocrine Systems
37. Animal Cardiovascular and Respiratory Systems
38. Animal Metabolism, Nutrition, and Digestion
39. Animal Renal Systems: Water and Waste
40. Animal Reproduction and Development
41. Animal Immune Systems
42. Animal Diversity

Case 8. Conserving Biodiversity: Rainforest and Coral Reef Hotspots

43. Behavior and Behavioral Ecology
44. Population Ecology
45. Species Interactions and Communities
46. Ecosystem Ecology
47. Biomes and Global Ecology
48. The Anthropocene: Humans as a Planetary Force

Authors

James Morris

James R. Morris is Professor of Biology at Brandeis University. He teaches a wide variety of courses for majors and non-majors, including introductory biology, evolution, genetics and genomics, epigenetics, comparative vertebrate anatomy, and a first-year seminar on Darwin’s On the Origin of Species. He is the recipient of numerous teaching awards from Brandeis and Harvard. His research focuses on the rapidly growing field of epigenetics, making use of the fruit fly Drosophila melanogaster as a model organism. He currently pursues this research with undergraduates in order to give them the opportunity to do genuine, laboratory-based research early in their scientific careers. Dr. Morris received a PhD in genetics from Harvard University and  an MD from Harvard Medical School. He was a Junior Fellow in the Society of Fellows at Harvard University, and a National Academies Education Fellow and Mentor in the Life Sciences. He also writes short essays on science, medicine, and teaching at his Science Whys blog (http://blogs.brandeis.edu/sciencewhys).


Daniel Hartl

Daniel L. Hartl is Higgins Professor of Biology in the Department of Organismic and Evolutionary Biology at Harvard University and Professor of Immunology and Infectious Diseases at the Harvard Chan School of Public Health. He has taught highly popular courses in genetics and evolution at both the introductory and advanced levels. His lab studies molecular evolutionary genetics and population genetics and genomics. Dr. Hartl is the recipient of the Samuel Weiner Outstanding Scholar Award as well as the Gold Medal of the Stazione Zoologica Anton Dohrn, Naples. He is a member of the National Academy of Sciences and the American Academy of Arts and Sciences. He has served as President of the Genetics Society of America and President of the Society for Molecular Biology and Evolution. Dr. Hartl’s PhD is from the University of Wisconsin, and he did postdoctoral studies at the University of California, Berkeley. Before joining the Harvard faculty, he served on the faculties of the University of Minnesota, Purdue University, and Washington University Medical School. In addition to publishing more than 400 scientific articles, Dr. Hartl has authored or coauthored 30 books.


Andrew Knoll

Andrew H. Knoll is Fisher Professor of Natural History in the Department of Organismic and Evolutionary Biology at Harvard University. He is also Professor of Earth and Planetary Sciences. Dr. Knoll teaches introductory courses in both departments. His research focuses on the early evolution of life, Precambrian environmental history, and the interconnections between the two. He has also worked extensively on the early evolution of animals, mass extinction, and plant evolution. He currently serves on the science team for NASA’s mission to Mars. Dr. Knoll received the Phi Beta Kappa Book Award in Science for Life on a Young Planet. Other honors include the Paleontological Society Medal and Wollaston Medal of the Geological Society, London. He is a member of the National Academy of Sciences and a foreign member of the Royal Society of London. He received his PhD from Harvard University and then taught at Oberlin College before returning to Harvard.


Robert Lue

Robert Lue is a professor of molecular and cellular biology and UNESCO Chair on Life Sciences and Social Innovation at Harvard University. He is also the Richard L. Menschel Faculty Director of the Derek Bok Center for Teaching and Learning, where he is responsible for fostering innovative teaching in Harvard’s Faculty of Arts and Sciences. Lue earned his Ph.D. in biology from Harvard, and since 1988 has taught undergraduate courses acclaimed for their innovative, interdisciplinary approach. In 2012, Lue’s extensive work on using technology to enhance learning took a new direction when he became the founding faculty director of HarvardX, Harvard’s university-wide online education initiative that includes the edX partnership with MIT. Lue continues to shape Harvard’s engagement in learning and expand its reach and impact globally. In 2017, he was awarded a grant from the Amgen Foundation to build LabXchange, an online platform for science education that integrates digital instruction and interactivity while connecting students, teachers, and researchers for sharing and collaboration. He also serves as the faculty director of the Harvard Ed Portal, the primary community engagement center on Harvard's Allston campus.


Melissa Michael

Melissa Michael is Director for Core Curriculum and Assistant Director for Undergraduate Instruction for the School of Molecular and Cellular Biology at the University of Illinois at Urbana-Champaign. A cell biologist, she primarily focuses on the continuing development of the School’s undergraduate curricula. She is currently engaged in several projects aimed at improving instruction and assessment at the course and program levels. Her research focuses primarily on how creative assessment strategies affect student learning outcomes, and how outcomes in large-enrollment courses can be improved through the use of formative assessment in active classrooms.


Andrew Berry

Andrew Berry is Lecturer in the Department of Organismic and Evolutionary Biology and an undergraduate advisor in the Life Sciences at Harvard University. With research interests in evolutionary biology and history of science, he teaches courses that either focus on one of the areas or combine the two. He has written two books: Infinite Tropics, a collection of the writings of Alfred Russel Wallace, and, with James D. Watson, DNA: The Secret of Life, which is part history, part exploration of the controversies surrounding DNA-based technologies.


Andrew Biewener

Andrew Biewener is Charles P. Lyman Professor of Biology in the Department of Organismic and Evolutionary Biology at Harvard University and Director of the Concord Field Station. He teaches both introductory and advanced courses in anatomy, physiology, and biomechanics. His research focuses on the comparative biomechanics and neuromuscular control of mammalian and avian locomotion, with relevance to biorobotics. He is currently Deputy Editor-in-Chief for the Journal of Experimental Biology. He also served as President of the American Society of Biomechanics.


Brian Farrell

Brian D. Farrell is Director of the David Rockefeller Center for Latin American Studies and Professor of Organismic and Evolutionary Biology and Curator in Entomology at the Museum of Comparative Zoology at Harvard University. He is an authority on coevolution between insects and plants and a specialist on the biology of beetles. He is the author of many scientific papers and book chapters on the evolution of ecological interactions between plants, beetles, and other insects in the tropics and temperate zone. Professor Farrell also spearheads initiatives to repatriate digital information from scientific specimens of insects in museums to their tropical countries of origin. In 2011–2012, he was a Fulbright Scholar to the Universidad Autónoma de Santo Domingo in the Dominican Republic. Professor Farrell received a BA degree in Zoology and Botany from the University of Vermont and MS and PhD degrees from the University of Maryland.


N. Michele Holbrook

N. Michele Holbrook is Charles Bullard Professor of Forestry in the Department of Organismic and Evolutionary Biology at Harvard University. She teaches an introductory course on biodiversity as well as advanced courses in plant biology. She studies the physics and physiology of vascular transport in plants with the goal of understanding how constraints on the movement of water and solutes between soil and leaves influences ecological and evolutionary processes.


Jean Heitz


Mark Hens


John Merrill


Randall Phillis


Debra Pires


Elena Lozovsky


Connected resources to help students connect How Life Works

Teaching you to think like a biologist, Biology: How Life Works provides you with the best resources to grasp modern biology. The text centers around six crucial themes--the scientific method, chemical and physical principles, cells, evolution, ecological systems, and human impact.

Also Available: Previous 2nd Edition

E-book

Read online (or offline) with all the highlighting and notetaking tools you need to be successful in this course.

Learn More

Achieve

Achieve is a single, easy-to-use platform proven to engage students for better course outcomes

Learn More

Launchpad

Get the e-book, do assignments, take quizzes, prepare for exams and more, to help you achieve success in class.

Learn More

Table of Contents

1. Life: Chemical, Cellular and Evolutionary Foundations

Case 1. The First Cell: Information, Homeostasis, and Energy

2. The Molecules of Life
3. Nucleic Acids and Transcription
4. Translation and Protein Structure
5. Organizing Principles: Lipids, Membranes, and Cell Compartments
6. Making Life Work: Capturing and Using Energy
7. Cellular Respiration: Harvesting Energy from Carbohydrates and Other Fuel Molecules
8. Photosynthesis: Using Sunlight to Build Carbohydrates

Case 2. Cancer: Cell Signaling, Form, and Division

9. Cell Signaling
10. Cell and Tissue Architecture: Cytoskeleton, Cell Junctions, and Extracellular Matrix
11. Cell Division: Variations, Regulation, and Cancer

Case 3. Your Personal Genome: You, from A to T

12. DNA Replication and Manipulation
13. Genomes
14. Mutation and Genetic Variation
15. Mendelian Inheritance
16. Inheritance of Sex Chromosomes, Linked Genes, and Organelles
17. The Genetic and Environmental Basis of Complex Traits
18. Genetic and Epigenetic Regulation
19. Genes and Development

Case 4. Malaria: Coevolution of Humans and a Parasite

20. Evolution: How Genotypes and Phenotypes Change Over Time
21. Species and Speciation
22. Evolutionary Patterns: Phylogeny and Fossils
23. Human Origins and Evolution

Case 5. The Human Microbiome: Diversity Within

24. Bacteria and Archaea
25. Eukaryotic Cells: Origins And Diversity
26. Being Multicellular

Case 6. Agriculture: Feeding a Growing Population

27. Plant Form, Function, and Evolutionary History
28. Plant Reproduction: Finding Mates and Dispersing Offspring
29. Plant Growth and Development
30. Plant Defense
31. Plant Diversity
32. Fungi

Case 7. Biology-Inspired Design: Using Nature to Solve Problems

33. Animal Form, Function, and Evolutionary History
34. Animal Nervous Systems
35. Animal Movement: Muscles and Skeletons
36. Animal Endocrine Systems
37. Animal Cardiovascular and Respiratory Systems
38. Animal Metabolism, Nutrition, and Digestion
39. Animal Renal Systems: Water and Waste
40. Animal Reproduction and Development
41. Animal Immune Systems
42. Animal Diversity

Case 8. Conserving Biodiversity: Rainforest and Coral Reef Hotspots

43. Behavior and Behavioral Ecology
44. Population Ecology
45. Species Interactions and Communities
46. Ecosystem Ecology
47. Biomes and Global Ecology
48. The Anthropocene: Humans as a Planetary Force

James Morris

James R. Morris is Professor of Biology at Brandeis University. He teaches a wide variety of courses for majors and non-majors, including introductory biology, evolution, genetics and genomics, epigenetics, comparative vertebrate anatomy, and a first-year seminar on Darwin’s On the Origin of Species. He is the recipient of numerous teaching awards from Brandeis and Harvard. His research focuses on the rapidly growing field of epigenetics, making use of the fruit fly Drosophila melanogaster as a model organism. He currently pursues this research with undergraduates in order to give them the opportunity to do genuine, laboratory-based research early in their scientific careers. Dr. Morris received a PhD in genetics from Harvard University and  an MD from Harvard Medical School. He was a Junior Fellow in the Society of Fellows at Harvard University, and a National Academies Education Fellow and Mentor in the Life Sciences. He also writes short essays on science, medicine, and teaching at his Science Whys blog (http://blogs.brandeis.edu/sciencewhys).


Daniel Hartl

Daniel L. Hartl is Higgins Professor of Biology in the Department of Organismic and Evolutionary Biology at Harvard University and Professor of Immunology and Infectious Diseases at the Harvard Chan School of Public Health. He has taught highly popular courses in genetics and evolution at both the introductory and advanced levels. His lab studies molecular evolutionary genetics and population genetics and genomics. Dr. Hartl is the recipient of the Samuel Weiner Outstanding Scholar Award as well as the Gold Medal of the Stazione Zoologica Anton Dohrn, Naples. He is a member of the National Academy of Sciences and the American Academy of Arts and Sciences. He has served as President of the Genetics Society of America and President of the Society for Molecular Biology and Evolution. Dr. Hartl’s PhD is from the University of Wisconsin, and he did postdoctoral studies at the University of California, Berkeley. Before joining the Harvard faculty, he served on the faculties of the University of Minnesota, Purdue University, and Washington University Medical School. In addition to publishing more than 400 scientific articles, Dr. Hartl has authored or coauthored 30 books.


Andrew Knoll

Andrew H. Knoll is Fisher Professor of Natural History in the Department of Organismic and Evolutionary Biology at Harvard University. He is also Professor of Earth and Planetary Sciences. Dr. Knoll teaches introductory courses in both departments. His research focuses on the early evolution of life, Precambrian environmental history, and the interconnections between the two. He has also worked extensively on the early evolution of animals, mass extinction, and plant evolution. He currently serves on the science team for NASA’s mission to Mars. Dr. Knoll received the Phi Beta Kappa Book Award in Science for Life on a Young Planet. Other honors include the Paleontological Society Medal and Wollaston Medal of the Geological Society, London. He is a member of the National Academy of Sciences and a foreign member of the Royal Society of London. He received his PhD from Harvard University and then taught at Oberlin College before returning to Harvard.


Robert Lue

Robert Lue is a professor of molecular and cellular biology and UNESCO Chair on Life Sciences and Social Innovation at Harvard University. He is also the Richard L. Menschel Faculty Director of the Derek Bok Center for Teaching and Learning, where he is responsible for fostering innovative teaching in Harvard’s Faculty of Arts and Sciences. Lue earned his Ph.D. in biology from Harvard, and since 1988 has taught undergraduate courses acclaimed for their innovative, interdisciplinary approach. In 2012, Lue’s extensive work on using technology to enhance learning took a new direction when he became the founding faculty director of HarvardX, Harvard’s university-wide online education initiative that includes the edX partnership with MIT. Lue continues to shape Harvard’s engagement in learning and expand its reach and impact globally. In 2017, he was awarded a grant from the Amgen Foundation to build LabXchange, an online platform for science education that integrates digital instruction and interactivity while connecting students, teachers, and researchers for sharing and collaboration. He also serves as the faculty director of the Harvard Ed Portal, the primary community engagement center on Harvard's Allston campus.


Melissa Michael

Melissa Michael is Director for Core Curriculum and Assistant Director for Undergraduate Instruction for the School of Molecular and Cellular Biology at the University of Illinois at Urbana-Champaign. A cell biologist, she primarily focuses on the continuing development of the School’s undergraduate curricula. She is currently engaged in several projects aimed at improving instruction and assessment at the course and program levels. Her research focuses primarily on how creative assessment strategies affect student learning outcomes, and how outcomes in large-enrollment courses can be improved through the use of formative assessment in active classrooms.


Andrew Berry

Andrew Berry is Lecturer in the Department of Organismic and Evolutionary Biology and an undergraduate advisor in the Life Sciences at Harvard University. With research interests in evolutionary biology and history of science, he teaches courses that either focus on one of the areas or combine the two. He has written two books: Infinite Tropics, a collection of the writings of Alfred Russel Wallace, and, with James D. Watson, DNA: The Secret of Life, which is part history, part exploration of the controversies surrounding DNA-based technologies.


Andrew Biewener

Andrew Biewener is Charles P. Lyman Professor of Biology in the Department of Organismic and Evolutionary Biology at Harvard University and Director of the Concord Field Station. He teaches both introductory and advanced courses in anatomy, physiology, and biomechanics. His research focuses on the comparative biomechanics and neuromuscular control of mammalian and avian locomotion, with relevance to biorobotics. He is currently Deputy Editor-in-Chief for the Journal of Experimental Biology. He also served as President of the American Society of Biomechanics.


Brian Farrell

Brian D. Farrell is Director of the David Rockefeller Center for Latin American Studies and Professor of Organismic and Evolutionary Biology and Curator in Entomology at the Museum of Comparative Zoology at Harvard University. He is an authority on coevolution between insects and plants and a specialist on the biology of beetles. He is the author of many scientific papers and book chapters on the evolution of ecological interactions between plants, beetles, and other insects in the tropics and temperate zone. Professor Farrell also spearheads initiatives to repatriate digital information from scientific specimens of insects in museums to their tropical countries of origin. In 2011–2012, he was a Fulbright Scholar to the Universidad Autónoma de Santo Domingo in the Dominican Republic. Professor Farrell received a BA degree in Zoology and Botany from the University of Vermont and MS and PhD degrees from the University of Maryland.


N. Michele Holbrook

N. Michele Holbrook is Charles Bullard Professor of Forestry in the Department of Organismic and Evolutionary Biology at Harvard University. She teaches an introductory course on biodiversity as well as advanced courses in plant biology. She studies the physics and physiology of vascular transport in plants with the goal of understanding how constraints on the movement of water and solutes between soil and leaves influences ecological and evolutionary processes.


Jean Heitz


Mark Hens


John Merrill


Randall Phillis


Debra Pires


Elena Lozovsky


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