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Biology: How Life Works, Volume 1 by James Morris; Daniel Hartl; Andrew Knoll; Robert Lue; Melissa Michael; Andrew Berry; Andrew Biewener; Brian Farrell; N. Michele Holbrook - Second Edition, 2016 from Macmillan Student Store
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Biology: How Life Works, Volume 1

Second  Edition|©2016  James Morris; Daniel Hartl; Andrew Knoll; Robert Lue; Melissa Michael; Andrew Berry; Andrew Biewener; Brian Farrell; N. Michele Holbrook

  • About
  • Contents
  • Authors

About

Learn to think like a biologist and gain a clearer understanding of modern biology, as Biology: How Life Works, Volume 1 explores the content with the framework of six crucial themes: the scientific method, chemical and physical processes, cells, evolution, ecological interactions, and human impact.

Contents

Table of Contents

  1. Life: Chemical, Cellular, and Evolutionary Foundations

Case 1 The First Cell: Life’s Origins

2. The Molecules of Life

New coverage of functional groups

3. Nucleic Acids and Transcription

Nucleotides now shown at physiological pH

4. Translation and Protein Structure

Amino acids now shown at physiological pH

5. Organizing Principles: Lipids, Membranes, and Cell Compartments

6. Making Life Work: Capturing and Using Energy

7. Cellular Respiration: Harvesting Energy from Carbohydrates and Other Fuel Molecules

8. Photosynthesis: Using Sunlight to Build Carbohydrates

The story of the evolution of photosynthesis now brought together in a single major section at the end of the chapter (Section 8.5).

Case 2: Cancer: When Good Cells Go Bad

9. Cell Signaling

10. Cell and Tissue Architecture: Cytoskeleton, Cell Junctions, and Extracellular Matrix

Chapters 9 and 10 have been streamlined to better match our mission statement.

11. Cell Division: Variations, Regulation, and Cancer

Case 3 You, From A to T: Your Personal Genome

12. DNA Replication and Manipulation

New inclusion of the trombone model of DNA replication

Addition of CRISPR technology

13. Genomes

Expanded coverage of retrotransposons and reverse transcriptase

14. Mutation and DNA Repair

15. Genetic Variation

16. Mendelian Inheritance

A new How Do We Know? figure explaining Mendel’s experimental results

17. Inheritance of Sex Chromosomes, Linked Genes, and Organelles

18. The Genetic and Environmental Basis of Complex Traits

19. Genetic and Epigenetic Regulation

New discussion of the mechanism of X-inactivation

20. Genes and Development

Case 4 Malaria: Coevolution of Humans and a Parasite

21. Evolution: How Genotypes and Phenotypes Change Over Time

An expanded discussion of nonrandom mating and inbreeding depression

22. Species and Speciation

23. Evolutionary Patterns: Phylogeny and Fossils

Addition of the effect of mass extinctions on species diversity

24. Human Origins and Evolution

Updated discussion of the relationship between Neanderthals and Homo sapiens, as well as Denisovans

Authors

James Morris

James Morris is Professor of Biology at Brandeis University. He teaches a wide variety of courses for majors and non-majors, including introductory biology, evolution, genetics and genomics, epigenetics, comparative vertebrate anatomy, and a first-year seminar on Darwin’s On the Origin of Species. He is the recipient of numerous teaching awards from Brandeis and Harvard. His research focuses on epigenetics. He currently pursues this research with undergraduates to give them the opportunity to do genuine, laboratory-based research. Dr. Morris received a PhD in genetics from Harvard University and an MD from Harvard Medical School. He was a Junior Fellow in the Society of Fellows at Harvard University and a National Academies Education Fellow and Mentor in the Life Sciences. He is also a reader for the AP® Biology exam and an author of Biology for the AP® Course.


Daniel Hartl

Daniel L. Hartl is Higgins Professor of Biology in the Department of Organismic and Evolutionary Biology at Harvard University and Professor of Immunology and Infectious Diseases at the Harvard T. H. Chan School of Public Health. He has taught highly popular courses in genetics and evolution at both the introductory and advanced levels. His lab studies molecular evolutionary genetics and population genetics and genomics. Dr. Hartl has been awarded the Thomas Hunt Morgan Medal from the Genetics Society of America, the Samuel Weiner Outstanding Scholar Award, and the Gold Medal of the Stazione Zoologica Anton Dohrn in Naples, Italy. He is a member of the National Academy of Sciences and the American Academy of Arts and Sciences. He has served as President of the Genetics Society of America and President of the Society for Molecular Biology and Evolution. Dr. Hartl’s PhD is from the University of Wisconsin, and he did postdoctoral studies at the University of California, Berkeley. Before joining the Harvard faculty, he served on the faculties of the University of Minnesota, Purdue University, and Washington University Medical School. In addition to publishing more than 450 scientific articles, Dr. Hartl has authored or coauthored 35 books.


Andrew Knoll

Andrew H. Knoll is Fisher Research Professor of Natural History in the Department of Organismic and Evolutionary Biology at Harvard University. He is also Professor of Earth and Planetary Sciences and taught introductory courses for many years in both departments. Dr. Knoll’s research focuses on the early evolution of life, Earth dynamic environmental history, and the interconnections between the two. He has also worked extensively on the early evolution of animals, mass extinction, and plant evolution, and he served on the science team for NASA’s MER mission to Mars. Dr. Knoll received the Phi Beta Kappa Book Award in Science for Life on a Young Planet. In 2018, he was awarded the International Prize for Biology and in 2022, he received the prestigious Crafoord Prize in Geosciences for his research on Earth’s early history. He is a member of the National Academy of Sciences and a foreign member of the Royal Society of London. Dr. Knoll received his PhD from Harvard University and taught at Oberlin College before returning to Harvard.


Robert Lue

Robert Lue was Professor of Molecular and Cellular Biology at Harvard University and the Richard L. Menschel Faculty Director of the Derek Bok Center for Teaching and Learning. Dr. Lue had a longstanding commitment to interdisciplinary teaching and research and chaired the faculty committee that developed the first integrated science foundation in the country to serve science majors as well as pre-medical students. The founding director of Life Sciences Education at Harvard, Dr. Lue led a complete redesign of the introductory curriculum, redefining how the university can more effectively foster new generations of scientists as well as science-literate citizens. Dr. Lue also developed award-winning multimedia, including the animation The Inner Life of the Cell. He coauthored undergraduate biology textbooks and chaired education conferences on college biology for the National Academies and the National Science Foundation and on diversity in science for the Howard Hughes Medical Institute and the National Institutes of Health. In 2012, Dr. Lue’s extensive work on using technology to enhance learning took a new direction when he became faculty director of university-wide online education initiative HarvardX. Dr. Lue earned his PhD from Harvard University.


Melissa Michael

Melissa Michael is Associate Director for Curriculum and Instruction in the School of Molecular and Cellular Biology at the University of Illinois at Urbana-Champaign. A cell biologist, Dr. Michael primarily focuses on the continuing development of the School’s undergraduate and graduate curricula. Her research focuses on the ways in which formative assessment strategies affect student learning outcomes in large-enrollment courses. She leads a new initiative to bring inclusive teaching practices to STEM courses. A member of the leadership for Mobile Summer Institutes for Scientific Teaching, she is now serving as an officer on the inaugural Executive Committee for the National Institute on Scientific Teaching.


Andrew Berry

Andrew Berry is Lecturer in the Department of Organismic and Evolutionary Biology and an undergraduate advisor in the Life Sciences at Harvard University. With research interests in evolutionary biology and history of science, he teaches courses that either focus on one of the areas or combine the two. He has written two books: Infinite Tropics, a collection of the writings of Alfred Russel Wallace, and, with James D. Watson, DNA: The Secret of Life, which is part history, part exploration of the controversies surrounding DNA-based technologies.


Andrew Biewener

Andrew Biewener is the Charles P. Lyman Professor of Biology in the Department of Organismic and Evolutionary Biology at Harvard University and Director of the Concord Field Station. He teaches both introductory and advanced courses in anatomy, physiology, and biomechanics. His research focuses on the comparative biomechanics and neuromuscular control of mammalian and avian locomotion, with relevance to biorobotics. He served as Deputy Editor-in-Chief for the Journal of Experimental Biology and has also served as President of the American Society of Biomechanics.


Brian Farrell

Brian D. Farrell is the Monique and Philip Lehner Professor for the Study of Latin America, a faculty member in the Department of Organismic and Evolutionary Biology, and Curator in Entomology at the Museum of Comparative Zoology at Harvard University. He is an authority on coevolution between insects and plants and a specialist on the biology of beetles. He teaches the large introductory course in organismic biology and a Freshmen Seminar in acoustic biology, and is interested in the impact of biophilia on human health. In 2011–2012, he was a Fulbright Scholar to the Universidad Autónoma de Santo Domingo in the Dominican Republic. Dr. Farrell received a BA in Zoology and Botany from the University of Vermont and MS and PhD from the University of Maryland.


N. Michele Holbrook

N. Michele Holbrook is Charles Bullard Professor of Forestry in the Department of Organismic and Evolutionary Biology at Harvard University, Head Tutor in Harvard’s undergraduate program in Environmental Policy and Public Policy, and Director of the Harvard Forest. She teaches introductory and advanced courses on plant biology and plant physiology, as well as courses on trees, forests, and climate change. Her research focuses on the physics and physiology of vascular transport in plants. Dr. Holbrook received her PhD from Stanford University.


Learn to think like a biologist and gain a clearer understanding of modern biology, as Biology: How Life Works, Volume 1 explores the content with the framework of six crucial themes: the scientific method, chemical and physical processes, cells, evolution, ecological interactions, and human impact.

Table of Contents

  1. Life: Chemical, Cellular, and Evolutionary Foundations

Case 1 The First Cell: Life’s Origins

2. The Molecules of Life

New coverage of functional groups

3. Nucleic Acids and Transcription

Nucleotides now shown at physiological pH

4. Translation and Protein Structure

Amino acids now shown at physiological pH

5. Organizing Principles: Lipids, Membranes, and Cell Compartments

6. Making Life Work: Capturing and Using Energy

7. Cellular Respiration: Harvesting Energy from Carbohydrates and Other Fuel Molecules

8. Photosynthesis: Using Sunlight to Build Carbohydrates

The story of the evolution of photosynthesis now brought together in a single major section at the end of the chapter (Section 8.5).

Case 2: Cancer: When Good Cells Go Bad

9. Cell Signaling

10. Cell and Tissue Architecture: Cytoskeleton, Cell Junctions, and Extracellular Matrix

Chapters 9 and 10 have been streamlined to better match our mission statement.

11. Cell Division: Variations, Regulation, and Cancer

Case 3 You, From A to T: Your Personal Genome

12. DNA Replication and Manipulation

New inclusion of the trombone model of DNA replication

Addition of CRISPR technology

13. Genomes

Expanded coverage of retrotransposons and reverse transcriptase

14. Mutation and DNA Repair

15. Genetic Variation

16. Mendelian Inheritance

A new How Do We Know? figure explaining Mendel’s experimental results

17. Inheritance of Sex Chromosomes, Linked Genes, and Organelles

18. The Genetic and Environmental Basis of Complex Traits

19. Genetic and Epigenetic Regulation

New discussion of the mechanism of X-inactivation

20. Genes and Development

Case 4 Malaria: Coevolution of Humans and a Parasite

21. Evolution: How Genotypes and Phenotypes Change Over Time

An expanded discussion of nonrandom mating and inbreeding depression

22. Species and Speciation

23. Evolutionary Patterns: Phylogeny and Fossils

Addition of the effect of mass extinctions on species diversity

24. Human Origins and Evolution

Updated discussion of the relationship between Neanderthals and Homo sapiens, as well as Denisovans

James Morris

James Morris is Professor of Biology at Brandeis University. He teaches a wide variety of courses for majors and non-majors, including introductory biology, evolution, genetics and genomics, epigenetics, comparative vertebrate anatomy, and a first-year seminar on Darwin’s On the Origin of Species. He is the recipient of numerous teaching awards from Brandeis and Harvard. His research focuses on epigenetics. He currently pursues this research with undergraduates to give them the opportunity to do genuine, laboratory-based research. Dr. Morris received a PhD in genetics from Harvard University and an MD from Harvard Medical School. He was a Junior Fellow in the Society of Fellows at Harvard University and a National Academies Education Fellow and Mentor in the Life Sciences. He is also a reader for the AP® Biology exam and an author of Biology for the AP® Course.


Daniel Hartl

Daniel L. Hartl is Higgins Professor of Biology in the Department of Organismic and Evolutionary Biology at Harvard University and Professor of Immunology and Infectious Diseases at the Harvard T. H. Chan School of Public Health. He has taught highly popular courses in genetics and evolution at both the introductory and advanced levels. His lab studies molecular evolutionary genetics and population genetics and genomics. Dr. Hartl has been awarded the Thomas Hunt Morgan Medal from the Genetics Society of America, the Samuel Weiner Outstanding Scholar Award, and the Gold Medal of the Stazione Zoologica Anton Dohrn in Naples, Italy. He is a member of the National Academy of Sciences and the American Academy of Arts and Sciences. He has served as President of the Genetics Society of America and President of the Society for Molecular Biology and Evolution. Dr. Hartl’s PhD is from the University of Wisconsin, and he did postdoctoral studies at the University of California, Berkeley. Before joining the Harvard faculty, he served on the faculties of the University of Minnesota, Purdue University, and Washington University Medical School. In addition to publishing more than 450 scientific articles, Dr. Hartl has authored or coauthored 35 books.


Andrew Knoll

Andrew H. Knoll is Fisher Research Professor of Natural History in the Department of Organismic and Evolutionary Biology at Harvard University. He is also Professor of Earth and Planetary Sciences and taught introductory courses for many years in both departments. Dr. Knoll’s research focuses on the early evolution of life, Earth dynamic environmental history, and the interconnections between the two. He has also worked extensively on the early evolution of animals, mass extinction, and plant evolution, and he served on the science team for NASA’s MER mission to Mars. Dr. Knoll received the Phi Beta Kappa Book Award in Science for Life on a Young Planet. In 2018, he was awarded the International Prize for Biology and in 2022, he received the prestigious Crafoord Prize in Geosciences for his research on Earth’s early history. He is a member of the National Academy of Sciences and a foreign member of the Royal Society of London. Dr. Knoll received his PhD from Harvard University and taught at Oberlin College before returning to Harvard.


Robert Lue

Robert Lue was Professor of Molecular and Cellular Biology at Harvard University and the Richard L. Menschel Faculty Director of the Derek Bok Center for Teaching and Learning. Dr. Lue had a longstanding commitment to interdisciplinary teaching and research and chaired the faculty committee that developed the first integrated science foundation in the country to serve science majors as well as pre-medical students. The founding director of Life Sciences Education at Harvard, Dr. Lue led a complete redesign of the introductory curriculum, redefining how the university can more effectively foster new generations of scientists as well as science-literate citizens. Dr. Lue also developed award-winning multimedia, including the animation The Inner Life of the Cell. He coauthored undergraduate biology textbooks and chaired education conferences on college biology for the National Academies and the National Science Foundation and on diversity in science for the Howard Hughes Medical Institute and the National Institutes of Health. In 2012, Dr. Lue’s extensive work on using technology to enhance learning took a new direction when he became faculty director of university-wide online education initiative HarvardX. Dr. Lue earned his PhD from Harvard University.


Melissa Michael

Melissa Michael is Associate Director for Curriculum and Instruction in the School of Molecular and Cellular Biology at the University of Illinois at Urbana-Champaign. A cell biologist, Dr. Michael primarily focuses on the continuing development of the School’s undergraduate and graduate curricula. Her research focuses on the ways in which formative assessment strategies affect student learning outcomes in large-enrollment courses. She leads a new initiative to bring inclusive teaching practices to STEM courses. A member of the leadership for Mobile Summer Institutes for Scientific Teaching, she is now serving as an officer on the inaugural Executive Committee for the National Institute on Scientific Teaching.


Andrew Berry

Andrew Berry is Lecturer in the Department of Organismic and Evolutionary Biology and an undergraduate advisor in the Life Sciences at Harvard University. With research interests in evolutionary biology and history of science, he teaches courses that either focus on one of the areas or combine the two. He has written two books: Infinite Tropics, a collection of the writings of Alfred Russel Wallace, and, with James D. Watson, DNA: The Secret of Life, which is part history, part exploration of the controversies surrounding DNA-based technologies.


Andrew Biewener

Andrew Biewener is the Charles P. Lyman Professor of Biology in the Department of Organismic and Evolutionary Biology at Harvard University and Director of the Concord Field Station. He teaches both introductory and advanced courses in anatomy, physiology, and biomechanics. His research focuses on the comparative biomechanics and neuromuscular control of mammalian and avian locomotion, with relevance to biorobotics. He served as Deputy Editor-in-Chief for the Journal of Experimental Biology and has also served as President of the American Society of Biomechanics.


Brian Farrell

Brian D. Farrell is the Monique and Philip Lehner Professor for the Study of Latin America, a faculty member in the Department of Organismic and Evolutionary Biology, and Curator in Entomology at the Museum of Comparative Zoology at Harvard University. He is an authority on coevolution between insects and plants and a specialist on the biology of beetles. He teaches the large introductory course in organismic biology and a Freshmen Seminar in acoustic biology, and is interested in the impact of biophilia on human health. In 2011–2012, he was a Fulbright Scholar to the Universidad Autónoma de Santo Domingo in the Dominican Republic. Dr. Farrell received a BA in Zoology and Botany from the University of Vermont and MS and PhD from the University of Maryland.


N. Michele Holbrook

N. Michele Holbrook is Charles Bullard Professor of Forestry in the Department of Organismic and Evolutionary Biology at Harvard University, Head Tutor in Harvard’s undergraduate program in Environmental Policy and Public Policy, and Director of the Harvard Forest. She teaches introductory and advanced courses on plant biology and plant physiology, as well as courses on trees, forests, and climate change. Her research focuses on the physics and physiology of vascular transport in plants. Dr. Holbrook received her PhD from Stanford University.


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